CD27 anticorps
Aperçu rapide pour CD27 anticorps (ABIN6297638)
Antigène
Voir toutes CD27 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Mouse anti-Human CD27 Antibody [Sodium Azide Free]
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Specificité
- Cell surface
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Purification
- Sezary cells were used as the immunogen for the CD27 antibody.
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Immunogène
- Sezary cells were used as the immunogen for the CD27 antibody.
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Indications d'application
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Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL -
Restrictions
- For Research Use only
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Buffer
- In 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- CD27 (CD27 Molecule (CD27))
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Autre désignation
- CD27 antigen
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Sujet
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Target Description: Recognizes a protein of a disulfide-linked 120 kDa dimer, identified as CD27 (Workshop VI, Code 6T-028). CD27 is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis.
Gene Symbol: CD27///TNFRSF7
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ID gène
- 939
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UniProt
- P26842
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Pathways
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
Antigène
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